Depression & Mood Disorders

Depression is a complex neurobiological condition that requires a thorough diagnostic evaluation and individualized treatment. Dr. DiFrancesco specializes in treatment-resistant cases, bringing deep pharmacological expertise to cases where standard treatments have not succeeded.

Conditions Addressed

• Major Depressive Disorder (MDD) — persistent depressed mood, loss of interest, and functional impairment
• Persistent Depressive Disorder (Dysthymia) — chronic, low-grade depression lasting years
• Treatment-Resistant Depression — depression that has not responded to standard antidepressants
• Seasonal Affective Disorder (SAD) — depression with a seasonal pattern
• Postpartum Depression — depression occurring after childbirth

Treatment Approach

Dr. DiFrancesco's neurobiological approach ensures accurate diagnosis and precise medication management. For treatment-resistant cases, she explores augmentation strategies and emerging pharmacological options, including emerging peptide-based approaches.